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followed by a stepwise progression to stronger centrally acting analgesics [5] . Analgesics can be broadly categorized as: non-opioid, opioid and adjuvant analgesics. Non-opioids may be used in combination with opioids for their opioid-sparing effect, permitting the use of lower doses of opioids [6] . Opioids are primarily used to treat moderate to severe pain that has not responded to non-opioids alone. Although opioids have a higher analgesic potency and wider range of indications
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